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Expression of MMP mRNA in primary HCECs. The increased mRNA expression of MMP-13 (A), MMP-9 (B), MMP-2 (C), MMP-3 (D) and MMP-7 (E) was observed in HCECs exposed to hyperosmotic media. Each bar represents mean±SD of 4 independent experiments. *P<0.05, **P<0.01, ***P<0.001, compared with normal control medium with 312 mOsM.
