Table 1.
Sample characteristics
| GCD |
GWAS Sample
|
Replication Sample (GWAS)
|
||||||
|---|---|---|---|---|---|---|---|---|
|
AA
|
EA
|
AA
|
EA
|
|||||
| Male | Female | Male | Female | Male | Female | Male | Female | |
| Recruiting site | ||||||||
| Yale (APT Foundation) | 652 | 627 | 626 | 398 | 222 | 197 | 474 | 477 |
| University of CT | 629 | 582 | 606 | 457 | 127 | 93 | 315 | 299 |
| MUSC | 95 | 193 | 85 | 76 | 21 | 24 | 47 | 47 |
| McLean Hospital | 54 | 42 | 60 | 41 | 0 | 2 | 2 | 3 |
| University of Pennsylvania | 297 | 147 | 20 | 10 | 51 | 64 | 43 | 39 |
|
AA
|
EA
|
AA
|
EA
|
|||||
| Male | Female | Male | Female | Male | Female | Male | Female | |
|
| ||||||||
| SAGE | 643 | 668 | 1222 | 1530 | ||||
| German Sample | 2367 | 1410 | ||||||
|
| ||||||||
| Counts for Analyses |
Cases
|
Controls
|
||||||
|
AA
|
EA
|
AA
|
EA
|
|||||
| Male | Female | Male | Female | Male | Female | Male | Female | |
|
| ||||||||
| Case–control | ||||||||
| GCD GWAS | 1022 | 717 | 900 | 523 | 454 | 709 | 213 | 283 |
| GCD Replication | 209 | 115 | 294 | 175 | 122 | 205 | 417 | 581 |
| SAGE | 413 | 263 | 761 | 485 | 230 | 405 | 461 | 1045 |
| German Sample | 1369 | 431 | 998 | 979 | ||||
| Ordinal trait | ||||||||
| GCD GWAS | 1727 | 1591 | 1397 | 982 | ||||
| GCD Replication | 421 | 380 | 881 | 865 | ||||
| SAGE | 643 | 668 | 1222 | 1530 | ||||