Table 3.

Comparison in mean change of QOL scores post-ESS in CRS patients with and without GERD.

	History of GERD
	Preoperative		Postoperative
QOL Improvement:	Mean (SD)	Range	Mean (SD)	Range	p-value
	(n=72)
RSDI physical subscale	19.4 (7.7)	[2 - 44]	10.0 (7.7)	[0 - 33]	<0.001
RSDI functional subscale	15.5 (8.4)	[0 - 36]	7.8 (7.4)	[0 - 32]	<0.001
RSDI emotional subscale	14.3 (8.9)	[0 - 37]	8.7 (8.2)	[0 - 39]	<0.001
RSDI total	49.3 (22.4)	[3 - 111]	26.5 (20.5)	[0 - 101]	<0.001
	(n=37)
CSS symptom subscale	22.8 (22.1)	[0 - 92]	60.8 (25.7)	[0 - 100]	<0.001
CSS medication subscale	47.3 (23.7)	[0 - 92]	59.5 (23.6)	[0 - 100]	0.021
CSS total	35.0 (17.4)	[0 - 80]	60.1 (21.1)	[12 - 88]]	<0.001
	(n=35)
SNOT-22	54.2 (18.0)	[26 - 99]	33.2 (18.6)	[3 - 76]	<0.001

	No GERD History
	Preoperative		Postoperative
QOL Improvement:	Mean (SD)	Range	Mean (SD)	Range	p-value
	(n=157)
RSDI physical subscale	19.5 (8.4)	[2 - 40]	10.3 (8.4)	[0 - 37]	<0.001
RSDI functional subscale	15.2 (7.3)	[0 - 36]	7.9 (7.8)	[0 - 35]	<0.001
RSDI emotional subscale	13.2 (7.8)	[0 - 40]	7.4 (7.6)	[0 - 40]	<0.001
RSDI total	47.8 (20.9)	[5 - 116]	25.6 (22.0)	[0 - 105]	<0.001
	(n=112)
CSS symptom subscale	29.2 (27.2)	[0 - 92]	60.9 (30.1)	[0 - 100]	<0.001
CSS medication subscale	47.4 (25.1)	[0 - 100]	58.2 (25.6)	[0 - 100]	<0.001
CSS total	38.3 (19.1)	[0 - 84]	59.6 (21.0)	[12 - 100]	<0.001
	(n=45)
SNOT-22	59.1 (20.7)	[15 - 106]	30.0 (23.0)	[2 - 104]	<0.001

QOL, quality of life; ESS, endoscopic sinus surgery; CRS, chronic rhinosinusitis; GERD, gastroesophageal reflux disease; SD, standard deviation; RSDI, Rhinosinusitis Disability Index; CSS, Chronic Sinusitis Survey; SNOT-22, 22-item Sinonasal Outcome Test