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. Author manuscript; available in PMC: 2014 Sep 16.
Published in final edited form as: Circ Res. 2012 Jul 25;111(8):991–1001. doi: 10.1161/CIRCRESAHA.112.268110

Table 1. Systolic BP and cardiac function of the RTEF-/- compared with the control littermates.

WT RTEF-/- p value WT p value RTEF-/- p value
NCD vs HFD NCD vs HFD
Body weight (g) NCD 28.4 ± 3.1 30 ± 1.1 0.23
HFD 37.2 ± 3.8 38.45 ± 2.6 0.43 0.0008 0.006
Body composition
Lean mass NCD 68.2 ± 5.2 69.72 ± 6 0.62
HFD 55.7 ± 5.4 49.81 ± 5.8 0.65 0.001 0.002
Fat mass NCD 12.2 ± 5.7 11.72 ± 7.1 0.41
HFD 29.9 ± 8.9 36.87 ± 6.6 0.52 0.0007 0.0002
Heart Rate (bpm) NCD 674.9 ± 55.7 704.8 ± 38.2 0.08
HFD 711.9 ± 32.6 736.7 ± 25.8* 0.03 0.12 0.0007
Systolic BP (mmHg) NCD 99.7 ± 3 109.1 ± 7 0.07
HFD 106.5 ± 5 111 ± 6 0.32 0.04 0.88
% FS NCD 51.0 ± 3.6 50 ± 1.4 0.57
HFD 45.8 ± 2.9 37.5 ± 6.2** 0.01 0.02 0.001
LVDd NCD 2.61 ± 0.1 3.21 ± 0.2** 0.01
HFD 3.5 ± 0.3 3.53 ± 0.2 0.11 0.89 0.07
LVDs NCD 1.27 ± 0.04 1.58 ± 0.06* 0.04
HFD 2.2 ± 0.03 1.64 ± 0.1** 0.0008 0.06 0.08
IVSd + LVPWd NCD 1.48 ± 0.06 1.44 ± 0.1 0.56
Total Wall Thickness HFD 1.3 ± 0.1 1.15 ± 0.2 0.74 0.04 0.04
IVSs NCD 1.6 ± 0.03 1.37 ± 0.08* 0.03
HFD 1.3 ± 0.04 1.1 ± 0.1** 0.01 0.00002 0.02
LVPWS NCD 1.3 ± 0.1 1.2 ± 0.1 0.6
HFD 1.0 ± 0.05 0.83 ± 0.09** 0.01 0.23 0.54