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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Trials Vaccinol. 2014;3:134–142. doi: 10.1016/j.trivac.2014.06.002

Table 2. Summary of lymphocytic infiltration in tumor tissues (under 20×object lens).

Group
(vaccine)
Rabbit ID Approximate cell numbers Outcome
(histology)
Tumor site 1 Tumor site 2
Group 1
(TT-E1 peptide)
3206 -(9) +(40) Persistent
3219 - (10) - (8) Persistent
2914 +(30) +(30) Persistent
3214 - (4) +(50) Persistent
Group 2
(E1 peptide)
3207 - (8) - (8) Persistent
3222 +(47) - (5) Persistent
2916 - (9) +(30) Persistent
3216 - (8) +(35) Persistent
Group 3
(E1 peptide-TT)
3210 - (8) +(30) Persistent
3223 +(>100) NA Small tumor
2917 NA NA Regressed
3217 - +(20) Persistent
Group 4
(TT-control)
3211 - (10) - (5) Early cancer*
3224 - (9) - (6) Early cancer
2918 - (10) - (4) Persistent
3218 +(20) - (1) Persistent

NA— the sites without tumors. Lymphocytes infiltration was graded from negative (- with infiltrated cells less than 10/field) to massive infiltration (more than 100/field, Figure 4A).

*

Early cancer was shown in Figure 4B by H&E histology staining