Table 1.
Demographic and clinical characteristics by MeDi group
| MeDi- | MeDi+ | |
|---|---|---|
| N | 32 | 20 |
| Age, y, mean (SD) | 53(13) | 55(12) |
| Gender, % female | 63% | 85% |
| Education, y, mean (SD) | 16(2) | 16(2) |
| Family history of LOAD, % positive | 69% | 60% |
| APOE ε4 status, % positive | 39% | 56% |
| Ethnicity | ||
| White | 83% | 80% |
| Black | 6% | 3% |
| Hispanic | 3% | 6% |
| Other | 8% | 11% |
| MeDi score [unitless] | 3.6(1.1) range 0-5 | 6.9(1.2) range 6-9 |
| Hypertension, % positive | 31% | 10% |
| HOMA-IR score [unitless] | 1.5(1.9) | 1.7(2.0) |
| Hip to waist ratio [unitless] | 1.18(0.12) | 1.16(0.11) |
| Blood pressure (mm/Hg) | ||
| Systolic | 117(15) | 122(12) |
| Diastolic | 69(15) | 69(18) |
| Glucose (mg/dl) | 76(9) | 81(15) |
| Cholesterol (mg/dl) | 193(35) | 206(41) |
| HDL: LDL ratio (unitless) | 0.6(0.2) | 0.5(0.2) |
| Triglycerids (mg/dl) | 86(34) | 96(49) |
| Homocysteine (micromol/l) | 10(2) | 10(3) |
| Neuropsychological tests | ||
| Mini Mental State Exam | 29(1) | 29(1) |
| Digit symbol substitution | 65(10) | 63(11) |
| Paired associates delayed recall | 7(2) | 6(3) |
| Paragraph delayed recall | 10(2) | 10(3) |
| Designs | 8(2) | 8(2) |
| Object naming | 55(12) | 53(13) |
| WAIS-vocabulary | 67(10) | 63(18) |
Values are mean (SD) unless otherwise specified; Abbreviations: MeDi = Mediterranean diet, lower (MeDi-) vs. higher (MeDi+) adherence