Table 1. Sequences and Predicted Helix Propensity for Peptides of α-Helix 3a.
constructs | sequences | helical content (%) |
---|---|---|
TGF-β1 | QYSKVLALYNQH | 4.8 |
TGF-β1 Q57T | TYSKVLALYNQH | 5.1 |
TGF-β1 Y58H | QHSKVLALYNQH | 2.6 |
TGF-β1 K60T | QYSTVLALYNQH | 5.2 |
TGF-β1 A63G | QYSKVLGLYNQH | 0.9 |
TGF-β1 Q67T | QYSKVLALYNTH | 3.8 |
TGF-β1 H68L | QYSKVLALYNQL | 4.4 |
TGF-β1 Y58H, A63G, Q67T | QHSKVLGLYNTH | 0.4 |
TGF-β3 | THSTVLGLYNTL | 0.5 |
TGF-β3 T57Q | QHSTVLGLYNTL | 0.5 |
TGF-β3 H58Y | TYSTVLGLYNTL | 0.7 |
TGF-β3 T60K | THSKVLGLYNTL | 0.5 |
TGF-β3 G63A | THSTVLALYNTL | 2.5 |
TGF-β3 T67Q | THSTVLGLYNQL | 0.7 |
TGF-β3 L68H | THSTVLGLYNTH | 0.5 |
TGF-β3 H58Y, G63A, T67Q | TYSTVLALYNQL | 5.0 |