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. Author manuscript; available in PMC: 2014 Sep 16.
Published in final edited form as: J Parkinsons Dis. 2012;2(3):215–223. doi: 10.3233/JPD-2012-012095

Table 2. Baseline Patient Characteristicsa.

At baseline, the mean age of subjects was 60 years old and the mean medication use was just over 2 years in both groups. The mean total UPDRS score in subjects randomized to DBS+ODT was 3 points higher than subjects randomized to ODT; mean UPDRS-III scores were nearly equal.

Characteristic ODT (n=15) ODT+DBS (n=15)
Gender
Male 13 14
Female 2 1
Age (yrs) at Enrollment
Mean 60 ± 7.0 60 ± 6.8
Range 51 - 69 52 - 74
Baseline Medicine Use
Mean Duration (yrs) 2.1 ± 1.1 2.2 ± 1.4
Mean L-dopa equivalents (mg/day)b 569 ± 389 451 ± 304
Baseline UPDRS Score
Mean Total 36 ± 15 39 ± 14
Mean UPDRS-III 15 ± 7.6 15 ± 8.5
a

Reprinted from PD Charles, RM Dolhun, CE Gill, TL Davis, MJ Bliton, MG Tramontana, RM Salomon, L Wang, P Hedera, FT Phibbs, JS Neimat, PE Konrad, Deep brain stimulation in early Parkinson's disease: Enrollment experience from a pilot trial, 18 / 3, 268-73, 2011, with permission from Elsevier.

b

100 mg of Levodopa with a dopa-decarboxlase inhibitor = 130 mg of controlled-release Levodopa reparations = 83 mg of Levodopa with dopa-decarboxylase and COMT inhibitors = 1 mg of pergolide, pramipexole or lisuride = 3 mg of ropinirole [20].