Wojtowicz JC |
2011 |
USA |
21/15 |
61 (29–84) |
20/16 |
Fish oil |
450 mg of eicosapentaenoic acid, 300 mg of docosahexaenoic acid 1000 mg of flaxseed oil |
Wheat germ oil |
Barabino S |
2003 |
Italy |
13/13 |
63.4±8.2/54.3±11.3 |
9:4/8:5 |
Drug |
LA (28.5 mg) and GLA (15 mg) twice daily |
Preservative-free substitute tears |
Manuel Neuzimar Pinheiro Jr |
2007 |
Brazil |
25/13 |
NA |
Women |
Flax seed |
Flaxseed oil capsules |
Basal oleic acid |
Haleh Kangari |
2013 |
Iran |
33/31 |
61.8±8/60.6±8.8 |
38/26 |
Drug |
180 mg of EPA and 120 mg DHA |
Medium-chain triglycerides |
Nikki Heidi Ong |
2013 |
USA |
9/9 |
31.1±6.2/32.1±10.6 |
12/6 |
Drug |
750 mg of omega-3 EFAs both eicosapentaenoic (EPA) docosahexaenoic acid (DHA), 1000 mg offlaxseed oil about 183 IU of vitamin E per day |
Same medical regimen |
Andrea Oleñik |
2013 |
Spain |
33/31 |
58/54 |
22: 9/24: 9 |
Drug |
DHA 350 mg, EPA 42.5 mg |
Placebo oral agent |
Kawakita T |
2013 |
Japan |
15/11 |
52.5±2.5/51.9±2.2 |
15/12 |
Fish oil |
EPA 1245 mg; DHA 540 mg |
Placebo supplement without EPA and DHA |