. Author manuscript; available in PMC: 2014 Sep 16.

Published in final edited form as: J Urol. 2010 Mar 19;183(5):2062–2069. doi: 10.1016/j.juro.2009.12.098

Table 3.

Effect of Patient Factors on Post-prostatectomy Outcomes, Univariate Analysis

Factor	Number of patients¹ (N=212)	Probability of 3-y recurrence-free surviva		Probability of 10-y survival

		%(95% CI)	P²	%(95% CI)	P²
Race, n(%)			0.7785		0.2738
White	208	88 (83–92)		76 (68–85)
Black	4	N/A³		N/A³
Age at diagnosis (years)			0.8123		0.3466
<60	86	89 (83–96)		N/A³
60–70	104	85 (78–92)		77 (63–90)
>70	22	81 (65–98)		36 (0–86)
Pre-prostatectomy PSA (ng/ml)			0.0430		0.5031
<4	22	N/A³		0 (0-0)
4–10	113	88 (82–94)		77 (64–90)
>10	43	84 (72–95)		N/A³
Gleason score			<0.001		0.0050
2–6	130	94 (89–98)		78 (66–90)
7	70	77 (67–87)		67 (42–93)
8–10	12	67 (40–93)		N/A³
Surgical margin			<0.001		0.3790
Negative	133	95 (91–98)		73 (62–85)
Positive	78	74 (64–84)		N/A³
Extracapsular extension			<0.001		0.4393
Negative	125	93 (88–97)		N/A³
Positive	67	76 (65–86)		72 (55–88)
Disease classification, n(%)			<0.001		0.0645
Clinically inapparent (T1)	8	71 (38–100)		N/A³
Confined within prostate (T2)	134	94 (90–98)		N/A³
Regional (T3)	57	71 (59–83)		64 (42–86)
EGFR rs884419 Genotype			0.0096		0.9665
G/G	156	89 (85–94)		74 (64–84)
A/G	34	88 (76–99)		0 (0-0)
A/A	6	N/A³		N/A³
EGFR rs7808697 Genotype			0.2161		0.2451
G/G	140	87 (81–92)		N/A³
A/G	39	87 (76–98)		71 (51–91)
A/A	5	N/A³		N/A³
EGFR rs845562 Genotype			0.7954		0.4686
G/G	132	89 (83–94)		N/A³
A/G	44	79 (67–91)		69 (48–89)
A/A	7	N/A³		N/A³
EGFR rs845560 Genotype			0.2611		0.0148
C/C	88	84 (76–92)		78 (65–91)
C/T	50	94 (87–100)		N/A³
T/T	20	89 (74–100)		N/A³
EGFR rs9642391 Genotype			0.7870		0.4411
C/C	20	N/A³		N/A³
C/G	59	82 (72–92)		72 (58–87)
G/G	115	89 (84–95)		N/A³
EGFR rs11976696 Genotype			0.1277		0.1195
G/G	10	60 (30–90)		N/A³
A/G	59	79 (69–90)		54 (10–98)
A/A	129	90 (85–96)		67 (51–84)
EGFR rs11543848 Genotype			0.5300		0.2001
G/G	110	88 (82–94)		69 (43–94)
A/G	42	85 (74–96)		64 (44–84)
A/A	10	N/A³		N/A³
EGFR rs7780270 Genotype			0.4841		0.9378
G/G	19	82 (64–100)		N/A³
G/T	17	N/A³		N/A³
T/T	6	N/A³		0 (0-0)
EGFR rs3735064 Genotype			0.8846		0.7085
C/C	86	88 (81–95)		70 (56–84)
C/T	37	84 (72–96)		N/A³
T/T	14	N/A³		0 (0-0)

Analyses were limited to patients for whom data were available

Raw P values for each factor were calculated by the log-rank test or from exact log-rank test (Race and EGFR rs884419)

Unable to calculate because all recurrence or death events occurred before 3-y or 10-y, respective