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. 2014 Sep 16;9(9):e106393. doi: 10.1371/journal.pone.0106393

Table 2. Effect of combination treatment on incidence of bacteremia and toxemia in study 1.

Bacteremia
Treatment Time Treatment* Time to Onset of Bacteremia (hours) Geometric Mean (Min, Max) Bacteremia Incidence** No. Positive/No. Animals (%)
Pre-Treatment Post-Treatment**
Control None 29.49 (22.00.39.52) 8/8 (100%) NA
30 hours Placebo+Levofloxacin 26.11 (22.35, 31.55) 7/8 (88%) 0/8 (0%)
AIGIV+Levofloxacin 27.36 (23.00,31.47) 8/8 (100%) 2/8 (25%)
36 hours Placebo+Levofloxacin 28.99 (23.47, 34.40) 4/8 (50%) 0/8 (0%)
AIGIV+Levofloxacin 23.94 (21.30, 27.47) 5/7 (71%) 0/7 (0%)
48 hours Placebo+Levofloxacin 27.29 (22.18, 42.18) 7/8 (88%) 1/8 (13%)
AIGIV+Levofloxacin 28.11 (25.02, 31.52) 6/8 (75%) 0/8 (0%)
60 hours Placebo+Levofloxacin 29.57 (25.23,34.03) 8/8 (100%) 0/8 (0%)
AIGIV+Levofloxacin 29.93 (23.93, 35.07) 8/8 (100%) 0/8 (0%)
Total 27.96 (21.30,42.18) 61/71 (86%) 3/63 (5%)
Placebo +Levofloxacin - 26/32 (81%) 1/32 (3%)
AIGIV +Levofloxacin - 27/31 (87%) 2/31 (6%)

NA- not applicable as animals were not treated.** data from all time points up to treatment (pre-treatment) and all time points post-treatment were combined for overall incidence.