Table 1. Prognostic clinicopathologic variables as predictors of disease-specific survival in 335 NSCLC patients (univariate analyses; log-rank test).
| Characteristics | Patients N, (%) | Median survival (months) | 5-year survival (%) | P |
| Age | .42 | |||
| ≤65 years | 156 (47) | 98 | 56 | |
| >65 years | 179 (53) | NR | 60 | |
| Sex | .22 | |||
| Female | 82 (24) | 190 | 64 | |
| Male | 253 (76) | 98 | 56 | |
| Smoking status | .26 | |||
| Never | 15 (5) | 19 | 43 | |
| Previous | 105 (31) | 84 | 55 | |
| Present | 215 (64) | NR | 60 | |
| WHO Performance status | .016 | |||
| 0 | 197 (59) | NR | 63 | |
| 1 | 120 (36) | 64 | 52 | |
| 2 | 18 (5) | 25 | 33 | |
| Weight loss | .76 | |||
| <10% | 303 (90) | 190 | 58 | |
| >10% | 32 (10) | 98 | 57 | |
| Histology | .028 | |||
| Squamous cell carcinoma | 191 (57) | NR | 66 | |
| Adenocarcinoma | 113 (34) | 54 | 46 | |
| Large cell carcinoma | 31 (9) | 98 | 56 | |
| Differentiation | <.001 | |||
| Poor | 138 (41) | 47 | 47 | |
| Moderate | 144 (43) | 190 | 65 | |
| Well | 53 (16) | NR | 68 | |
| Surgical procedure | 0.007 | |||
| Wedge + Lobectomy | 243 (73) | 190 | 62 | |
| Pneumectomy | 92 (27) | 37 | 47 | |
| p-Stage | <.001 | |||
| pI | 157 (47) | NR | 72 | |
| pII | 136 (41) | 62 | 51 | |
| pIIIA | 42 (12) | 17 | 24 | |
| T-status | <.001 | |||
| 1 | 85 (25) | 190 | 75 | |
| 2 | 188 (56) | 84 | 57 | |
| 3 | 62 (19) | 25 | 37 | |
| N-status | <.001 | |||
| 0 | 232 (69) | NR | 67 | |
| 1 | 76 (23) | 35 | 43 | |
| 2 | 27 (8) | 18 | 18 | |
| Surgical margins | .37 | |||
| Free | 307 (92) | 190 | 59 | |
| Not free | 28 (8) | 47 | 48 | |
| Vascular infiltration | .001 | |||
| No | 284 (85) | 190 | 62 | |
| Yes | 51 (15) | 27 | 33 |
NR, not reached.