Table 4.

Summary of MBF and CFR estimation performance

	Microsphere	Distributed	Two- compartment	Three- compartment
Relative dispersion in normal regions	13%	14%	16%	13%
RMSE model solution (kBq/mL)		0.125 ± .005	0.26 ± .01*	0.19 ± .008*
Blood flow estimation
Mean of error# (mL/g/minute)		0.03 ± 0.04	−0.31 ±0.03*	−0.03 ± 0.03
Standard deviation of error (mL/g/minute)		0.67	0.52*	0.53*
Slope of regression		0.98 [0.88, 1.08]	0.64 [0.57, 0.71]*	0.69 [0.62, 0.76]*
Correlation coefficient		0.74	0.74	0.74
Blood flow SEE (mL/g/minute)		0.67	0.61	0.52
CFR estimation
Mean of error*		0.23 ± 0.08	0.14 ± 0.07*	0.16 ±0.07
Standard deviation of error		0.92	0.88	0.82
Slope of regression		0.92 [0.81, 1.03]	0.73 [0.63, 0.82]*	0.58 10.52, 0.65]*
Correlation coefficient		0.81	0.78	0.81
CFR SEE		0.95	0.89	0.83

^*Significant difference between distributed metric and compartment metric.

^#Mean ± standard error of mean presented.