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Active matrix metalloproteinase (MMP)-9 (82 kDa) was determined by scanning densitometry. Interleukin-1β (IL-1β) stimulates MMP-9 and MMP-2, and trypsine converts latent form of MMP-2 and -9 into active form. Vitamin D, 25(OH)D, and 1,25(OH)2D inhibit the activation of MMP induced by trypsin.
