Table 2. Input parameters for probabilistic sensitivity analysis of immunological staging by POC-CD4 versus LAB-CD4 in Mozambique.

Variable	Distribution	Base Case Value	SD	Reference
Repeat HIV testing or immunologic staging (years)	Log-normal	10	4.8	Assumption
Cost per point-of-care CD4 test (US dollars)	Log-normal	24	6	[39],[40]
Overall linkage to care after POC-CD4 (percent)a	Beta	61	9.8	Adapted from [14]
Annual routine care costs ratio (percent)b	Log-normal	100	25	Adapted from [46]
Mean CD4 at diagnosis (cells/µl)	Log-normal	300	150	[14]
Point-of-care test CV (percent)c	Beta	32.6	10	[36]
Linkage after WHO stage 3 or 4 OI (percent)	Beta	75	12.5	Assumption
Mean age at diagnosis (years)	Log-normal	32.7	7.5	[14]
Linkage after TB (percent)	Beta	43	10	[33],[34]

^aOverall linkage is varied using point-of-care test completion (83%, SD 13.5%).

^bAnnual routine care costs for patients with CD4 count ≤250/µl are US$250 (SD US$62.5), and for patients with CD4 count>250/µl are US$160 (SD US$40).

^cPoint-of-care test sensitivity (87%–95%) and specificity (76%–96%).