Table 2. Results of Linear Mixed Models Analysis Showing Associations between the Major Study Variables over 6 Weeks over the Course of RT for HNC (N=49 patient-caregiver dyads).

Major Study Variables		B¹	SE	t	Lower 95% Limit	Upper 95% Limit
MDASI Core Severity
	Intercept	1.01	.30
	Time	.11	.06	1.85	-.01	.24
	MDASI HN Severity	.60	.05	11.37^***	.49	.70
	Intercept	1.48	.47
	Time	.26	.08	3.15^**	.09	.43
	Patient Distress	.37	.07	5.14^***	.23	.51
	Intercept	2.05	.62
	Time	.31	.11	2.9^**	.08	.55
	Caregiver Distress	.28	.07	3.86^***	.13	.42
	Intercept	2.24	.94
	Time	.33	.13	2.61^*	.06	.60
	Caregiver Burden	.55	.31	1.76	-.08	1.18
MDASI HN Severity
	Intercept	.69	.51
	Time	.26	.08	3.06^**	.08	.44
	Patient Distress	.64	.08	8.27^***	.48	.79
	Intercept	2.04	.79
	Time	.32	.11	2.85^*	.07	.56
	Caregiver Distress	.39	.08	5.00^***	.23	.54
	Intercept	2.15	1.18
	Time	.34	.13	2.66^*	.06	.61
	Caregiver Burden	.83	.38	2.23^*	.09	1.58
Patient Distress
	Intercept	8.96	.87
	Time	.34	.18	1.92	-.05	.72
	Caregiver Distress	-.56	.07	-8.24^***	-.69	-.42
	Intercept	4.43	1.16
	Time	.32	.08	4.12^***	.15	.50
	Caregiver Burden	.36	.34	1.06	-.32	1.05
Caregiver Distress
	Intercept	5.27	1.22
	Time	.18	.19	.93	-.12	.58
	Caregiver Burden	.24	.42	.58	-.60	1.09

Note.

With the exception of caregiver burden, all scales were 0-10. A one unit increase in the predictor is equal to the corresponding increase/decrease in the raw coefficient value for the outcome; B=raw coefficient, SE=standard error,

p<.05,

^**

p<.01,

^***

p<.001