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. Author manuscript; available in PMC: 2015 Oct 1.
Published in final edited form as: Stem Cells. 2014 Oct;32(10):2690–2701. doi: 10.1002/stem.1760

Figure 3. NK cell infiltration into spinal cords following allogeneic NPC transplantation.

Figure 3

Vehicle only or eGFP-NPCs were transplanted into JHMV-infected C57BL/6 (syngeneic transplant) and JHMV-infected BALB/c (allogeneic transplant) mice on day 14 post-JHMV-infection. (A) Mice were sacrificed at day 8 p.t. and the frequency of NKG2D+ NK cells among total lymphocytes in the spinal cord (9mm rostral and caudal to transplant site) of recipient mice was determined by flow cytometry. Representative flow analysis of CD3−CD49b+NKG2D+ NK cells in syngeneic and allogeneic eGFP-NPC transplanted, and vehicle only transplanted mice is shown. (B) Quantification of NK cells in allogeneic and syngeneic transplanted mice normalized to vehicle only transplant. Data is presented as average±SEM and is 1 of 2 representative experiments with a minimum of 3 mice per group; p<0.01.