Table 7.

BNP, Symptoms, Quality of Life, and 6 Minute Walk

	Greater LVMi Regression (n=344)	Lesser LVMi Regression (n=346)	p-value
BNP
Baseline	862 (398, 2258)	932 (450, 1927)	0.92
30 days	624 (305, 1497)	727 (350, 1599)	0.27
6 months	421 (211, 1024)	562 (243, 1287)	0.08
1 year	356 (186, 824)	533 (268, 1068)	0.002
NYHA class III/IV
Baseline	94%	94%	0.98
Discharge	35%	42%	0.09
30 days	18%	19%	0.87
6 months	10%	11%	0.60
1 year	8%	13%	0.11
KCCQ
Baseline
Number of subjects with KCCQ data	n=313	n=318
Overall summary score	42.3 ± 21.8	44.7 ± 22.6	0.18
30 days
Number of subjects with KCCQ data	n=318	n=314
Overall summary score adjusted for baseline score	61.0 ± 24.5	62.7 ± 24.4	0.75**
6 months
Number of subjects with KCCQ data	n=278	n=277
Overall summary score adjusted for baseline score	73.2 ± 21.4	70.5 ± 23.9	0.44**
1 year
Number of subjects with KCCQ data	n=228	n=236
Overall summary score adjusted for baseline score	73.0 ± 21.2	71.5 ± 22.3	0.06**
6 minute walk
Baseline
Could not perform	32%	34%	0.61
Distance walked (m)*	151 ± 101	166 ± 96	0.12
30 days
Could not perform	29%	29%	0.19
Distance walked (m)	187 ± 110	180 ± 110	0.48
6 months
Could not perform	22%	24%	0.55
Distance walked (m)	206 ± 114	209 ± 114	0.79
1 year
Could not perform	20%	22%	0.47
Distance walked (m)	201 ± 97	200 ± 123	0.92

Data reported as mean±SD, median (25^th, 75^th percentiles), or %.

^*Excluding those who could not perform the 6 minute walk.

^**Follow-up KCCQ overall summary scores were compared using analysis of covariance to adjust for baseline differences in KCCQ scores between groups.

Abbreviations: LVMi, left ventricular mass index; BNP, B-type natriuretic peptide; NYHA, New York Heart Association; KCCQ, Kansas City Cardiomyopathy Questionnaire.