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Immunological phenotype of patients treated at different Ig administration intervals. (a) IgA serum levels; (b) percentages of peripheral blood switched B memory B cells (CD19 + CD27 + IgM-IgD-) in PAD patients grouped according to the replacement intervals of IVIG administration: 1-week, 2-weeks, 3-weeks, 4-weeks. Statistical differences between groups are shown
