Table 2.
Methodological assessment of included trials
| Study ID | Adequacy of sequence generation | Allocation concealment | Blinding of participants and personnel | Blinding of outcome assessment | Incomplete outcome data |
|---|---|---|---|---|---|
| Francavilla et al. [9] | (+) | (+) | (+) | (+) | (+) |
| Dinleyici et al. [5] | (+) | (+) | (−) | (?) | (−) |
| Gutierrez-Castrellon et al. [12] | (+) | (+) | (+) | (?) | (+) |
| Wanke et al. [31] | (+) | (+) | (+) | (+) | (+) |
| Savino et al. [24] | (+) | (−) | (+) | (+) | (+) |
| Szajewska et al. [26] | (+) | (+) | (+) | (+) | (+) |
| Sung et al. [25] | (+) | (+) | (+) | (+) | (−) |
| Coccorullo et al. [4] | (+) | (?) | (+) | (?) | (?) |
| Romano et al. [22] | (+) | (+) | (+) | (+) | (?) |
| Indrio et al. [14] | (+) | (+) | (+) | (+) | (−) |
| Indrio et al. (2013) [13] | (+) | (+) | (+) | (+) | (+) |
| Garofoli et al. [10] | (+) | (?) | (+) | (?) | (?) |
| Rojas et al. [21] | (+) | (+) | (+) | (+) | (+) |
| Oncel et al. [19] | (+) | (+) | (+) | (+) | (+) |
(+) indicates a low risk of bias, (−) indicates a high risk of bias, and (?) indicates unclear risk of bias