Table 1. Primary screen.

Compound Source	No. of Compounds
Validation Library (Microsource, Prestwick and CMLD)	5,067
ChemBridge Library	43,736
ChemDiv Library	56,232
Orthogonally compressed library (LCGC)	16,000
Total No. of compounds	121,035

Actives: 232.

Overall hit rate: 0.19%.