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. 2014 Sep 16;9(9):e107006. doi: 10.1371/journal.pone.0107006

Table 3. EC50, IC50 and therapeutic index for seven cherry-picked compounds.

Firefly Luciferase Cytotoxicity
Compound ID EC50 (µM) Fold-induction IC50 (µM) Therapeutic Index
1 1.4 8.6 >100 >100
7 5.9 6.5 87.6 15
42 9.8 5.2 >100 >100
87 49.3 9.6 >100 >100
125 5.7 7.0 35.0 6
157 30.0 9.5 >100 >100
208 14.3 10.1 24.3 2

>100: Less than 10% or no cytotoxicity up to 100 µM tested.