Table 2.
Characteristics of breast cancer patients diagnosed in 2005, 2008 and 2011 in Catalonia, Spain, according to type of surgery
| Conservative surgery | Radical surgery | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2005 | 2008 | 2011 | 2005 | 2008 | 2011 | |||||||||
| n | (%) | n | (%) | n | (%) | β* (95% CI) | n | (%) | n | (%) | n | (%) | β* (95% CI) | |
| Age | ||||||||||||||
| ≤49 | 528 | (26.2) | 614 | (26.3) | 583 | (23.7) | -0.017 (-0.034; -0.001) | 267 | (28.0) | 301 | (34.0) | 293 | (33.8) | 0.030 (0.008;0.053) |
| 50- 69 | 1005 | (49.8) | 1229 | (52.7) | 1343 | (54.5) | 0.015 (0.006; 0.024) | 339 | (35.6) | 282 | (31.9) | 299 | (34.5) | -0.006 (-0.027; 0.016) |
| ≥ 70 | 485 | (24.0) | 490 | (21.0) | 537 | (21.8) | -0.016 (-0.034; 0.003) | 347 | (36.4) | 302 | (34.1) | 275 | (31.7) | -0.023 (-0.044;-0.002) |
| Stage | cp | |||||||||||||
| Local | 1849 | (91.6) | 2072 | (88.8) | 2039 | (82.8) | -0.016 (-0.020; -0.013) | 864 | (90.7) | 722 | (81.6) | 646 | (74.5) | -0.033 (-0.040;-0.026) |
| Regional | 153 | (7.6) | 250 | (10.7) | 398 | (16.2) | 0.128 (0.100; 0.157) | 73 | (7.7) | 131 | (14.8) | 184 | (21.2) | 0.161 (0.122; 0.201) |
| Distant | 16 | (0.8) | 11 | (0.5) | 26 | (1.1) | 0.064 (-0.047; 0.179) | 16 | (1.7) | 32 | (3.6) | 37 | (4.3) | 0.141 (0.054; 0.230) |
| Charlson Comorbidity Index | ||||||||||||||
| No comorbidity | 1718 | (85.1) | 1947 | (83.5) | 1995 | (81.0) | -0.008 (-0.013; -0.004) | 772 | (81.0) | 704 | (79.5) | 679 | (78.3) | -0.006 (-0.013;0.002) |
| Low comorbidity | 243 | (12.0) | 305 | (13.1) | 355 | (14.4) | 0.030 (0.005; 0.055) | 132 | (13.9) | 135 | (15.3) | 130 | (15.0) | 0.013 (-0.024;0.050) |
| High comorbidity | 57 | (2.8) | 81 | (3.5) | 113 | (4.6) | 0.082 (0.031; 0.134) | 49 | (5.1) | 46 | (5.2) | 58 | (6.7) | 0.045 (-0.018;0.108) |
| Type of surgery | ||||||||||||||
| Tumorectomy/Partial mastectomy | 2018 | (100.0) | 2333 | (100.0) | 2463 | (100.0) | - | - | - | - | - | - | ||
| Simple mastectomy | - | - | - | - | - | - | 812 | (85.2) | 757 | (85.5) | 719 | (82.9) | -0.004 (-0.011;0.002) | |
| Radical mastectomy | - | - | - | - | - | - | 124 | (13.0) | 107 | (12.1) | 110 | (12.7) | -0.005 (-0.045;0.306) | |
| Subcutaneous mastectomy | - | - | - | - | - | - | 17 | (1.8) | 21 | (2.4) | 38 | (4.4) | 0.157 (0.064; 0.254) | |
| Lymph node removal | 1556 | (77.1) | 1990 | (85.3) | 2122 | (86.2) | 0.016 (0.012; 0.021) | 830 | (87.1) | 783 | (88.5) | 776 | (89.5) | 0.005 (-0.001;0.010) |
| Type of lymph node removal 1 | ||||||||||||||
| Simple | 759 | (48.8) | 1349 | (67.8) | 1516 | (71.4) | 0.070 (0.061; 0.079) | 528 | (63.6) | 559 | (71.4) | 526 | (67.8) | 0.015 (0.002;0.027) |
| Radical | 797 | (51.2) | 641 | (32.2) | 606 | (28.6) | -0.082 (-0.097;-0.067) | 302 | (36.4) | 224 | (28.6) | 250 | (32.2) | -0.018 (-0.042;0.007) |
| Hospital complexity | ||||||||||||||
| Low | 309 | (15.3) | 422 | (18.1) | 466 | (18.9) | 0.034 (0.012; 0.055) | 172 | (18.0) | 138 | (15.6) | 153 | (17.6) | -0.005 (-0.039;0.029) |
| Medium | 892 | (44.2) | 1068 | (45.8) | 1193 | (48.4) | 0.015 (0.005; 0.026) | 405 | (42.5) | 390 | (44.1) | 420 | (48.4) | 0.022 (0.005;0.039) |
| High | 817 | (40.5) | 843 | (36.1) | 804 | (32.6) | -0.036 (-0.049;-0.023) | 376 | (39.5) | 357 | (40.3) | 294 | (33.9) | -0.023 (-0.043;-0.004) |
| In-hospital deaths 2 | 1 | (0.0) | 0 | (0.0) | 2 | (0.1) | 0.144 (-0.355; 0.749) | 4 | (0.4) | 1 | (0.1) | 1 | (0.1) | -0.260 (-0.718; 0.088) |
| Discharge destination | ||||||||||||||
| Domicile | 2008 | (99.5) | 2328 | (99.8) | 2451 | (99.5) | 0 (-0.001; 0.001) | 943 | (99.0) | 872 | (98.5) | 848 | (97.8) | -0.002 (-0.004; 0.001) |
| With support | 9 | (0.4) | 4 | (0.2) | 11 | (0.4) | 0.009 (-0.156; 0.178) | 8 | (0.8) | 11 | (1.2) | 19 | (2.2) | 0.164 (0.032;0.304) |
| Other3 | 1 | (0.0) | 1 | (0.0) | 1 | (0.0) | -0.033 (-0.535; 0.469) | 2 | (0.2) | 2 | (0.2) | 0 | (0.0) | -0.260 (-0.850;0.162) |
| Total 4 | 2018 | (67.9) | 2333 | (72.5) | 2463 | (74.0) | 0.014 (0.009; 0.019) | 953 | (32.1) | 885 | (27.5) | 867 | (26.0) | -0.035 (-0.048;-0.022) |
*β is the slope of the log-binomial model used to measure the temporal trend; 95% CI: 95%Confidence Interval; In bold, statistically significant; 1Percentages were calculated taking into account the total number of lymph node removal; 2Mortality within 30 days after admission; 3Includes hospital mortality during hospitalization (in-hospital mortality); 4Percentages were calculated taking into account the total number of surgical patients in the respective years.