Table 2.

Adjusted incidence rate ratios (IRR) of atopic dermatitis (AD) according to type of early infection

			IRR (95% CI) of AD associated with infection*
	AD cases†	Person years†	Both sexes	Boys‡	Girls‡
Type of infection§:
Cold lasting ≥3 days	895/1743	12 429/21 634	1.07 (0.98 to 1.17)	0.98 (0.87 to 1.10)	1.19 (1.04 to 1.35)
Diarrhoea lasting ≥3 days	99/2539	1055/33 004	1.38 (1.13 to 1.69)	1.18 (0.89 to 1.58)	1.63 (1.28 to 2.17)
Otitis media	95/2543	1255/32 804	1.14 (0.92 to 1.40)	1.15 (0.88 to 1.50)	1.13 (0.82 to 1.57)
Pneumonia	54/2584	704/33 356	1.12 (0.85 to 1.46)	0.98 (0.69 to 1.40)	1.39 (0.91 to 2.13)
Chickenpox	47/2591	639/33 420	1.06 (0.79 to 1.42)	1.18 (0.80 to 1.73)	0.94 (0.60 to 1.46)
Exanthema subitum	33/2605	405/33 654	1.26 (0.89 to 1.78)	1.59 (1.03 to 2.45)	0.93 (0.53 to 1.65)
Admitted to hospital for infection	142/2496	1 771/32 290	1.11 (0.94 to 1.34)	1.04 (0.84 to 1.30)	1.23 (0.94 to 1.61)
Total No of infections:
0	1571	19 321	1 (ref)	1 (ref)	1 (ref)
1	536	7 807	1.00 (0.90 to 1.10)	0.95 (0.83 to 1.09)	1.07 (0.92 to 1.24)
2	280	4 020	1.09 (0.96 to 1.25)	1.07 (0.90 to 1.28)	1.11 (0.91 to 1.36)
≥3	251	2 912	1.33 (1.16 to 1.53)	1.15 (0.95 to 1.40)	1.56 (1.28 to 1.91)
Increase per infection	—	—	1.08 (1.04 to 1.13)	1.04 (0.98 to 1.40)	1.13 (1.06 to 1.30)

^*Adjusted for parental history of allergy, sex, number of siblings, season of birth, maternal age, and maternal education.

^†Figures are exposed/not exposed, unless indicated otherwise.

^‡Obtained in independent analyses. Adjusted for parental history of allergy, number of siblings, season of birth, maternal age, and maternal education.

^§Data on specific infections presented for diseases reported by more than 250 children.