Table 1. Animal ID, route of infection, viral load at set point, observation time, and MHC and TLR7 genotype.

Animal ID	Route of infection*	Plasma viral RNA copies ml−1 at 24/26 weeks p.i.	Survival (weeks p.i.)	Disease course predicted by MHC class I genotype	Homozygous for MHC class II DQB1-DRB haplotype	TLR7 genotype associated with slow disease progression†
Controllers
1937	I.v.	Negative	>64‡	Rapid	Yes	Yes
1939	Tonsils	Negative	>26‡	Slow	No	Yes
1964	I.v.	Negative	>26‡	Rapid	Yes	Yes
1982	I.v.	Negative	>26‡	Slow	Yes	Yes
8638	Tonsils	Negative	>62	Unknown	No	No
8785	I.v.	Negative	>64‡	Unknown	Yes	Yes
8790	I.v.	220, 32 weeks p.i. Negative	>64‡	Moderate	Yes	No
9026	I.v.	Negative	>64‡	Moderate	No	Yes
Non-controllers
1891	I.v.	29 000	102	Unknown	Yes	Yes
1948	I.v.	54 000	100	Unknown	No	Heterozygous
1961	Tonsils	7900	84	Unknown	No	Yes
1968	Tonsils	1000	>26‡	Unknown	Yes	No
1969	i.v.	3200	>26‡	Rapid	No	No
8637	Tonsils	680	>62‡	Unknown	No	Yes
8768	I.v.	560	180	Unknown	Yes	Yes
9037	Tonsils	1400	>26‡	Unknown	No	Yes
9038	I.v.	2500	185	Unknown	No	No
Transfused
1891T	Material from Mm1891; i.v.	1200	58	Unknown	No	Yes
1948T	Material from Mm1948; i.v.	1600	61	Moderate	No	No

^*I.v., Intravenous; tonsils, atraumatic via tonsils.

^†TLR7 genotype associated with slow disease progression: c.−17C, c.13G (Siddiqui et al., 2011).

^‡Animals were challenged with SIVmac251 at the indicated time point and excluded from further analysis.