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. 2014 Sep 17;16(1):67. doi: 10.1186/s12968-014-0067-z

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© Xie et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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A case study of a symptomatic subject with an atherosclerotic plaque of 70% stenosis in the right internal carotid artery. Pre-contrast T2-weighted image showed slightly hyper-intense signal throughout the plaque area. Pre-contrast T1-weighted image was iso-intense in the plaque area. Post-contrast T1-weighted image showed a clear hypo-intense area within the plaque, a typical LRNC appearance, surrounded by enhanced fibrous plaque tissue. DWI (b = 300 mm²/s) using DP-TSE showed a hyper-intense region, i.e. low diffusion, that spatially matched to the LRNC area in the post-contrast T1-weighted image. ADC map showed an area with low diffusion (0.62 ± 0.15 × 10⁻³ mm²/s) within the plaque that spatially matched to the LRNC finding in the post-contrast T1-weighted image.