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. 2014 Sep 10;14:496. doi: 10.1186/1471-2334-14-496

Table 5.

Factors associated with the presence of thrombocytopenia

Results of uni- and multivariable log-binomial regression models
Covariate Univariable (n = 400) Multivariable‡ (n = 397*)
PR (95% CI) p value PR (95% CI) p value
Sex
  Male 1 1
  Female 0.33 (0.16 to 0.69) 0.003 0.32 (0.15 to 0.68) 0.003
HAART status at recruitment§
  Not on HAART 1 1
  On HAART 0.35 (0.16 to 0.76) 0.009 0.32 (0.14 to 0.75) 0.008
CD4 count cells/μl
  <50 1
  50 to < 200 0.40 (0.17 to 0.95) 0.037
  ≥ 200** 0.48 (0.18 to 1.33) 0.159
BMI
  under weight 1
  normal 0.90 (0.25 to 3.20) 0.873
  over weight 0.67 (0.16 to 2.75) 0.575
  Incomplete information* - -
Age, years
  18 to < 30 1
  30 to < 35 2.36 (0.76 to 7.34) 0.139
  35 to < 41 1.74 (0.57 to 5.27) 0.328
  ≥ 41 1.74 (0.56 to 5.40) 0.335
Education level
  None 1
  Minimum Primary 1.05 (0.13 to 8.63) 0.961
  Minimum Secondary 1.02 (0.12 to 8.62) 0.983
  Tertiary 0.58 (0.05 to 7.00) 0.667
  Don’t know - -
Employment status
  Unemployed 1
  Employed 2.62 (0.61 to 11.3) 0.196
Marital status
  Not married 1
  Married 1.50 (0.73 to 3.09) 0.274
Presence/history of oral candidiasis
  No 1
  Yes 1.44 (0.66 to 3.15) 0.358
Presence/history of fever
  No 1
  Yes 1.01 (0.50 to 2.06) 0.975

Multivariable model only includes variables for which data are shown below because all others were lacking significance.

§All participants on HAART were categorized into one group for this analysis because none of the 15 patients on AZT had thrombocytopenia.

AZT = azidothymidine or zidovudine.

*Three participants with missing BMI could not be included in the log-binomial regression model because the outcome did not vary in this group.

**CD4 categories 200 to <350 and ≥ 350 were combined for this analysis because none of the participants with CD4 count ≥ 350 had thrombocytopenia.