Table 2.
Molecular breast cancer subtypes by tumor histopathology (Total number N = 269)
| |
Luminal A |
Luminal B |
HER2/neu |
TN |
p |
||||
|---|---|---|---|---|---|---|---|---|---|
| N | % | N | % | N | % | N | % | ||
|
Tumor size, cm (T category; T1: ≤ 2.0 cm; T2: > 2.0 cm ≤ 5.0 cm; T3: > 5.0 cm)
1
| |||||||||
| T1 |
32 |
52.46 |
49 |
41.88 |
14 |
35.90 |
10 |
22.73 |
0.0803 |
| T2 |
26 |
42.62 |
57 |
48.72 |
22 |
56.41 |
31 |
70.45 |
|
| T3 |
3 |
4,92 |
11 |
9.40 |
3 |
7.69 |
3 |
6.82 |
|
| Missing |
3 |
|
3 |
|
0 |
|
2 |
|
|
|
Lymph node status | |||||||||
| Positive |
22 |
43.14 |
41 |
40.20 |
13 |
41.94 |
19 |
51.35 |
0.7067 |
| Negative |
29 |
56.86 |
61 |
59.80 |
18 |
58.06 |
18 |
48.65 |
|
| Missing |
13 |
|
18 |
|
8 |
|
9 |
|
|
|
Distant metastases | |||||||||
| Positive |
9 |
16.36 |
14 |
12.73 |
6 |
18.18 |
8 |
17.78 |
0.7922 |
| Negative |
46 |
83.64 |
96 |
87.27 |
27 |
81.82 |
37 |
82.22 |
|
| Missing |
9 |
|
10 |
|
6 |
|
1 |
|
|
|
Histological grade | |||||||||
| Low (G1) |
11 |
21.57 |
14 |
13.59 |
1 |
2.94 |
1 |
2.86 |
< 0.0001 |
| Inter. (G2) |
38 |
74.51 |
76 |
73.79 |
21 |
61.77 |
22 |
62.86 |
|
| High (G3) |
2 |
3.92 |
13 |
12.62 |
12 |
35.29 |
12 |
34.28 |
|
| Missing |
14 |
|
17 |
|
5 |
|
11 |
|
|
|
Ki67 positive cells (%) | |||||||||
| Mean | 6.05 ± 0.467 | 36.71 ± 1.819 | 36.43 ± 4.120 | 50.38 ± 4.691 | < 0.0001 | ||||
1Pair wise comparison of Luminal A and TN: p = 0.0088; Luminal B and TN: p = 0.0448.