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Direct comparison of the selected 5 min (A) and 60 min (B) biodistribution data between 99mTc-P6D-RGD2, 99mTc-P6G-RGD2, and 99mTc-3P-RGD2 in athymic nude mice bearing U87MG glioma xenografts to illustrate the impact of linkers (D3 versus G3 and PEG4) between the two c(RGDfK) moieties on the uptake of 99mTc-labeled cyclic RGD peptide dimers in tumor and normal organs.
