TABLE 1.
Placebo N = 111 | E10 N = 118 | L10 N = 116 | E20 N = 111 | L20 N = 109 | L10 + E10 N = 116 | L10 + E20 N = 118 | L20 + E10 N = 110 | L20 + E20 N = 116 | Overall N = 1025 | |
Males (%) | 50.5 | 47.5 | 44.8 | 48.6 | 44.0 | 49.1 | 52.5 | 48.2 | 45.7 | 47.9 |
Age (years) | 54.7 ± 9.8 | 54.8 ± 9.9 | 53.6 ± 9.8 | 52.1 ± 9.4 | 55.4 ± 9.7 | 54.0 ± 10.2 | 53.0 ± 10.1 | 51.9 ± 10.2 | 55.8 ± 10.1 | 53.9 ± 9.10 |
White (%) | 99.1 | 99.2 | 99.1 | 99.1 | 100 | 100 | 99.2 | 100 | 99.1 | 99.4 |
BMI (kg/m2) | 29.89 ± 4.9 | 29.34 ± 5.2 | 30.60 ± 4.9 | 30.12 ± 5.2 | 29.73 ± 4.8 | 30.38 ± 4.8 | 29.72 ± 4.8 | 29.86 ± 4.7 | 29.11 ± 5.3 | 29.86 ± 4.10 |
Office SBP (mmHg) | 160.5 ± 10.5 | 158.8 ± 10.3 | 159.5 ± 10.4 | 159.9 ± 9.7 | 159.2 ± 10.7 | 159.1 ± 10.2 | 159.4 ± 10.5 | 158.6 ± 10.4 | 159.0 ± 10.7 | 159.3 ± 10.4 |
Office DBP (mmHg) | 103.2 ± 2.4 | 103.2 ± 2.2 | 102.9 ± 2.5 | 103.1 ± 2.6 | 103.3 ± 2.8 | 103.0 ± 2.6 | 102.9 ± 3.4 | 102.8 ± 3.1 | 103.1 ± 3.10 | 103.1 ± 2.9 |
Office HR (b/min) | 77.6 ± 10.8 | 77.3 ± 11.0 | 77.8 ± 9.3 | 77.9 ± 10.6 | 78.5 ± 9.9 | 79.4 ± 9.5 | 78.7 ± 11.7 | 78.4 ± 11.3 | 77.1 ± 9.9 | 78.1 ± 10.5 |
Data are shown as % or as mean ± standard deviation (SD). E, enalapril; HR, heart rate; ITT, intention to treat; L, lercanidipine.