FIG 3 .

Lack of effect of IL-1 signaling on phagocytosis and bactericidal activity. (A) Whole blood (0.2 ml) from WT or IL-1RI KO mice was infected with 2.5 × 10⁴ GBS, and bacteria were enumerated at the time points indicated after incubation at 37°C. Phagocytosis (B) and killing (C) of GBS by bone marrow-derived macrophages from WT and IL-1RI^−/− mice are also shown. Data are expressed as means ± standard deviations of three duplicate observations, each from a different experiment.