FIG 7 .

Effect of IL-1 signaling on chemokine production and neutrophil recruitment during GBS infection. KC, MIP-1α, IL-1β, and MPO protein levels (A to D) or CFU counts (E) were measured in organ homogenates from WT and IL-1RI^−/− mice at the times indicated after i.v. infection with 1 × 10⁸ CFU of GBS. (A to D) Data are expressed as means ± standard deviations of three duplicate observations, each conducted with a different animal, in the course of a single experiment. (E) Horizontal bars indicate mean values. *, P < 0.05 versus WT mice, as determined by one-way analysis of variance and the Student-Keuls-Newman test.