Table 2.
Adverse effects of arsenic trioxide-based therapy in relapsed/refractory myeloma patients
| Reference | Hematological (%)
|
Nonhematological (%)
|
|||||||
|---|---|---|---|---|---|---|---|---|---|
| Anemia | Neutropenia | Thrombocytopenia | Cardiac | Gastrointestinal (diarrhea, vomiting, stomatitis) | Hepatic | Renal | Skin rash | Fever/infections | |
| Hussein et al48 | 9 | 17 | 79 | 25 | 33 | ||||
| Yan et al50 | 5 | 5 | 19 | 5 | |||||
| Abou-Jawde et al27 | 5 | ||||||||
| Baz et al49 | |||||||||
| Berenson et al26 | 5 | 2 | 6 | 6 | 2 | 2 | 22 | ||
| Berenson et al25 | 5 | 15 | 14 | ||||||
| Wu et al28 | 20 | 10 | 15 | 50 | |||||
| Dey et al23 | |||||||||
| Qazilbash et al24 | 6 | 52 | 2 | 6 | 4 | 23 | |||
| Zhang and Bao44 | |||||||||