Table 1.
Comparison of ESBL-EC and ESBL-KP with respect to molecular characteristics and susceptibility profiles
| ESBL-EC (%) | ESBL-KP (%) | P value | |
|---|---|---|---|
|
aac(6’)-Ib-cr |
41/95 (43.1) |
61/81 (75.3) |
<0.0001 |
|
qnrB |
11/95 (11.6) |
65/81 (80.2) |
<0.0001 |
|
blaCTX-M-15 |
58/95 (61.1) |
70/81 (86.4) |
0.0002 |
|
blaCTX-M-14 |
28/95 (29.5) |
2/81 (2.5) |
<0.0001 |
|
blaTEM-1 |
53/95 (55.8) |
20/81 (24.7) |
<0.0001 |
|
blaOXA |
42/95 (44.2) |
50/81 (61.7) |
0.024 |
| Other blaCTX-M |
4/95 (4.2) |
1/81 (1.2) |
0.38 |
| Non blaCTX-M ESBLs |
5/95 (5.3) |
8/81 (9.9) |
0.26 |
| Gentamicin NS |
53/95 (55.8) |
66/81 (81.5) |
0.0003 |
| Trimethoprim-sulfamethoxazole NS |
67/95 (70.5) |
78/81 (96.3) |
<0.0001 |
| Fluoroquinolone NS |
66/95 (69.5) |
62/81 (76.5) |
0.31 |
| NS ≥ 4 antibiotic classes | 36/95 (37.9) | 55/81 (67.9) | <0.0001 |
NS, non-susceptible. Representative antibiotics for the three non-beta-lactam antibiotic classes tested were: gentamicin; trimethoprim-sulfamethoxazole, ciprofloxacin. All isolates were assumed by definition to be resistant to cephalosporins.