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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: J Neuroendocrinol. 2014 Sep;26(9):573–586. doi: 10.1111/jne.12179

Figure 3.

Figure 3

Dual fluorescence confocal image to show overlap in nuclear Fos-ir (red) and cytoplasmic tryptophan hydroxylase (TPH; green) staining within the dorsal raphe nucleus (A). Solid arrows show doubly labeled neurons and open arrowheads mark Fos-positive, TPH-negative cells. Mean ± SEM relative numbers of double-labeled (Fos + TPH) neurons within the dorsal subdivision of the dorsal raphe nucleus in males and females (B). Scatterplot showing a significant negative correlation between plasma estradiol concentrations and Fos + TPH-labeled cells in the DRD of WAY females (C). **P < 0.01 vs. vehicle counterpart (n = 7–8 per group). Adapted with permission from Goel et al (83).