Mean ± SEM 5HT1A BPND during the placebo and E2-replacement for DOM, long SERT genotype Red bars, DOM, short SERT genotype(s-variant) Grey bars, SUB long SERT genotype Black bars, and SUB short SERT genotype (s-variant) females Blue bars. (A) Hippocampal 5HT1A BPND is attenuated in subordinate females during the placebo condition compared to dominant females (denoted by asterisk), an effect that is normalized upon E2 replacement. (B) Letters denote that hypothalamic 5HT1A BPND is attenuated in subordinate females during the placebo condition compared to dominant females, an effect that is reversed upon E2 replacement.(144)