Table 4.

Adjusted hazard ratios for gastric cancer by intensity and duration of current cigarette smoking

Smoking intensity	Cases	Hazard ratio	95% CI
Men (n = 40,453)	172
Never smoker	88	1.00
Current smoker (cigarettes/day)
≤10	27	1.89	1.20–2.95
11–20	33	1.76	1.16–2.67
21+	24	2.15	1.34–3.48
p for trend	0.0004
Women (n = 70,855)	188
Never smoker	148	1.00
Current smoker (cigarettes/day)
≤10	22	1.88	1.18–2.99
11–20	12	1.50	0.82–2.75
21+	6	2.15	0.92–5.01
p for trend	0.0166
Total (n = 111,308)a	360
Never smoker	236	1.00
Current smoker (cigarettes/day)
≤10	49	1.87	1.36–2.58
11–20	45	1.68	1.19–2.35
21+	30	2.16	1.43–3.26
p for trend	<0.0001
Smoking duration
Men (n = 40,453)	172
Never smoker	88	1.00
Current smoker (years)
≤30	23	1.97	1.21–3.21
31–40	23	2.14	1.32–3.49
41+	38	1.75	1.17–2.61
p for trend		0.0005
Women (n = 70,855)	188
Never smoker	148	1.00
Current smoker (years)
≤30	14	1.51	0.85–2.67
31–40	10	1.59	0.82–3.07
41+	16	2.29	1.34–3.92
p for trend		0.0014
Total (n = 111,308)a	360
Never smoker	236	1.00
Current smoker (years)
≤30	37	1.74	1.20–2.51
31–40	33	1.91	1.30–2.81
41+	54	1.89	1.37–2.60
p for trend		<0.0001

Adjusted for age at cohort entry as a continuous variable, ethnicity, education, processed meat intake, BMI, alcohol intake, aspirin use, and family history of gastric cancer

Former smokers are not included in this analysis

^aAdditional adjustment for sex