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. 2014 Sep 2;2014:627181. doi: 10.1155/2014/627181

Figure 2.

Figure 2

Hydrogen peroxide (H2O2)-induced endothelial dysfunction is reversed by catalase and NADPH oxidase inhibitors. (a) Representative traces of acetylcholine- (ACh-) induced endothelium-dependent relaxation (EDR) in H2O2- (200 μM) treated rings with catalase (20000 U/mL), apocynin (10 μM), or diphenyleneiodonium (DPI, 10 nM) pretreatment. (b) Effects of catalase, apocynin, and DPI on H2O2-provoked disruption of ACh-induced EDR. Data represent the mean ± the standard error of the mean (SEM) of 4–6 independent experiments (*P < 0.05 versus control; # P < 0.05 versus H2O2).