Table 2.

Effects of catalase, apocynin, and DPI on H₂O₂-provoked endothelial dysfunction in isolated rat aortic rings.

Treatment	pD2	E max⁡ (%)	N
Control	7.22 ± 0.07	5.32 ± 2.93	4
H2O2 (200 μM)	4.63 ± 0.25∗	59.88 ± 6.44∗	6
Catalase (20000 U/mL) + H2O2	6.10 ± 0.07#	26.11 ± 6.34#	4
Apocynin (10 μM) + H2O2	6.51 ± 0.13#	27.31 ± 10.51#	4
DPI (10 nM) + H2O2	6.33 ± 0.09#	16.88 ± 8.82#	4

Data represent the mean ± the SEM of 4–6 independent experiments (*P < 0.05 versus control; ^# P < 0.05 versus H₂O₂).

DPI: diphenyleneiodonium; E _max⁡: maximal response; H₂O₂: hydrogen peroxide; pD₂: negative logarithm of the EC₅₀; SEM: standard error of the mean.