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. 2014 Sep 16;9(9):e107743. doi: 10.1371/journal.pone.0107743

Figure 2. Receiver-operating characteristic curve analysis of anti-neutrophil cytoplasmic antibodies (ANCAs) to proteinase 3 (PR3) and myeloperoxidase (MPO) by CytoBead ANCA.

Figure 2

465 sera from 118 patients with ANCA-associated vasculitis, 133 with rheumatoid arthritis, 49 with infectious diseases, 20 with Crohn's disease, 20 with autoimmune hepatitis and 125 blood donors were included. PR3- and MPO-ANCA were determined simultaneously by microbead immunoassay employing 90 patients with granulomatosis with polyangiitis and 28 patients with microscopic polyangiitis as positive criterion, respectively.