TABLE 1.

Baseline Characteristics: Randomized Subjects

Baseline Characteristic	Control (n = 29, 62% male) Mean (SD), range	rhGH (n = 33, 66.7% male) Mean (SD), range
Chronologic age, yr	9.4 (2.2.), 5.4 to 13.2	9.4 (2.0), 5.2 to 13.4
Bone age, yr	7.8 (2.2), 3.0 to 11.5	7.7 (2.0), 3.5 to 11.5
Weight, kg	24.8 (5.8), 15.8 to 38.6	24.2 (5.0), 14.7 to 35.1
Height, cm	123.2 (11.8), 104.5 to 144.6	123.3 (10.2), 100.4 to 143.8
Height SDS	−1.9 (0.6), −3.5 to −1.2	−1.8 (0.4), −2.9 to −1.2
Total lean body mass, kg	19.1 (4.0), 12.3 to 28.0	18.4 (3.9), 11.7 to 26.5
6-minute walk distance, m	519.6 (133.3), 228.0 to 747.0	491.1 (119.5), 251.0 to 731.0
IGF-I, ng/mL	124.0 (54.3), 35.0 to 254.0	122.4 (56.9), 38.0 to 286
Pulmonary Function
FEV1, mL	1400.3 (495.3), 660.0 to 2620.0	1209.1 (450.5), 310.0 to 2620.0
FEV1 % predicted	94.6 (18.5), 52.8 to 128.5	81.9 (24.5), 28.6 to 125.2
FVC, mL	1692.4 (595.9), 700.0 to 3230.0	1555.8 (456.7), 860.0 to 2950.0
FVC % predicted	102.2 (18.6), 54.6 to 146.6	94.2 (18.2), 57.3 to 125.4

FEV₁, forced expiratory volume in 1 second; FVC, forced vital capacity; IGF-I, insulin-like growth factor-I; rhGH, recombinant human growth hormone; SD, standard deviation; SDS, standard deviation score