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. Author manuscript; available in PMC: 2014 Sep 18.
Published in final edited form as: Annu Rev Pathol. 2010;5:99–118. doi: 10.1146/annurev-pathol-121808-102144

Figure 2.

Figure 2

Human fibroblasts, either presenescent (PRE) or senescent (SEN), were immunostained for the inflammatory cytokines interleukin (IL)-6 and IL-8, as well as the senescence marker p16. Cells were made senescent either by replicative exhaustion (REP) or ionizing radiation (IR) or by expression of oncogenic RAS (RAS).