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. Author manuscript; available in PMC: 2014 Sep 18.
Published in final edited form as: Comb Chem High Throughput Screen. 2014 Mar;17(3):210–230. doi: 10.2174/1386207317666140109121546

Figure 3. Daily Amlexanox gavage both prevents and reverses diet induced or genetic obesity.

Figure 3

a) Body weight of preventative group. Mice gavaged with Amlexanox at 25 mg/kg or 100 mg/kg or vehicle control (HFD and ND). Initiation of gavage in the preventative group coincided with high fat diet (HFD) feeding at 8 weeks of age. b) Body weight of treatment group. Mice treated with 25 mg/kg Amlexanox or vehicle control after 12 weeks HFD feeding. Mice maintained on ND and gavaged with vehicle control are also shown.