Table 2.
FCM | Placebo | Source | |
---|---|---|---|
Proportion of patients according to NYHA class at baseline | |||
NYHA class II |
0.17 |
0.19 |
Anker 2009 [16] |
NYHA class III |
0.83 |
0.81 |
Anker 2009 [16] |
Proportion of patients according to NYHA class at 24 weeks | |||
NYHA class I |
0.06 |
0.01 |
Anker 2009 [16] |
NYHA class II |
0.41 |
0.29 |
Anker 2009 [16] |
NYHA class III |
0.5 |
0.65 |
Anker 2009 [16] |
NYHA class IV |
0.01 |
0.03 |
Anker 2009 [16] |
Death |
0.02 |
0.03 |
Anker 2009 [16] |
Total medication cost (IDA treatment cost) |
US $645 |
0 |
|
FCM price (500 mg vial) |
US $160 |
0 |
Suggested price |
Dose |
1,000 mg |
0 |
KNF |
No. of infusions |
2 |
0 |
Gutzwiller 2012 [19] |
Normal saline price (200 mL) |
US $1.8 |
0 |
HIRA weighted price |
Infusion fee |
US $1.1 |
0 |
NHI fee schedule |
Adjusted CHF medical cost by NYHA class excluding cost of IV iron treatment (6 months) | |||
NYHA class I |
US $510 |
US $510 |
See Table 1 |
NYHA class II |
US $928 |
US $928 |
See Table 1 |
NYHA class III |
US $1,623 |
US $1,623 |
See Table 1 |
NYHA class IV |
US $3,142 |
US $3,142 |
See Table 1 |
Utility weight according to NYHA class (1 year) | |||
NYHA class I |
0.93 |
0.93 |
Fox 2007 [21] |
NYHA class II |
0.78 |
0.78 |
Fox 2007 [21] |
NYHA class III |
0.61 |
0.61 |
Fox 2007 [21] |
NYHA class IV |
0.44 |
0.44 |
Fox 2007 [21] |
Utility difference from the FAIR-HF study | 0.037 (scenario 2) | Gutzwiller 2012 [19] |
FCM, ferric carboxymaltose; IDA, iron-deficiency anemia; KNF, Korean National Formulary; NYHA, New York Heart Association; NHI, national health insurance; No, Number; IV, intravenous.