Table 1.
miRNA With Increased Expression in Cholangiocarcinoma
| miRNA | Target | Tumor Cell Lines | Human CCA | Animal Models | References |
|---|---|---|---|---|---|
| miR-21 | PDCD4, PTEN, TIMP-3,RECK | KMCH-1, Mz-ChA-1, TFK, RBE, QBC939 | CCA | (4,6,8–13,36–38) | |
| miR-421 | FXR | HCCC-9180, SSP25, RBE | CCA | (14) | |
| miR-200b | PTPN12 | KMCH-1, Mz-ChA-1, TFK | (not described) | (4) | |
| miR-26a | GSK-3β | SG231, TFK, HuCCT1, CCLP-1 | CCA | (3) | |
| miR-141 | CLOCK | KMCH-1, Mz-ChA-1, TFK | (not described) | (4) | |
| miR-210(mouse) | Mnt | (not described) | (not described) | mouse CCA | (5) |
| miR-let7a | NF2 | KMCH-1, Mz-ChA-1 | (not described) | (44) | |
| miR-125a-5p | DUSP6 (putative) | HuH28, HuCCT1 | (not described) | (27) | |
| miR-31 | RASA1 | HCCC-9810 | iCCA | (6,7) | |
| miR-25 | TRAIL death receptor-4 | KMCH-1, Mz-ChA-1 | (not described) | (23) | |
| miR-151-3p | (not described) | CCA | (45) | ||
| miR-223 | (not described) | iCCA | (6) | ||
| miR-135b, miR-106b, miR-30e, miR-30b, miR-151-3p, miR-10a, miR-181a, miR-96, miR-221 | (not described) | CCA | (38) |