Table 1. Baseline characteristics of patients according to the area of capillary nonperfusion on fluorescein angiography.
| Variable | Overall | Nonperfusion <10 DA (nonischemic DR) | Nonperfusion ≥10 DA (ischemic DR) | P |
|---|---|---|---|---|
| No of patients | 51 | 27 | 24 | |
| Age (years) | 58.2±12.4 | 56.7±13.9 | 59.9±10.4 | 0.363 |
| Men (%) | 60.8 | 70.4 | 50.0 | 0.137 |
| Hypertension | ||||
| History of HTN (%) | 80.4 | 70.4 | 91.7 | 0.056 |
| Duration of HTN (years) | 5.4±4.9 | 4.1±3.6 | 6.6±5.6 | 0.088 |
| SBP (mm Hg) | 138.4±20.7 | 133.6±18.7 | 142.4±21.8 | 0.164 |
| DBP (mm Hg) | 80.2±10.5 | 81.2±10.8 | 79.4±10.4 | 0.582 |
| Diabetes | ||||
| Duration of diabetes (years) | 12.7±8.6 | 10.8±7.6 | 14.6±9.4 | 0.126 |
| HbA1c (%) | 8.4±2.1 | 8.4±1.9 | 8.2±2.2 | 0.752 |
| Serum creatinine (mg/dl) | 1.7±1.2 | 1.2±0.5 | 2.2±1.5 | 0.005 |
| eGFR (ml/min/1.73 m2) | 55.0±29.6 | 67.8±30.1 | 40.7±21.7 | 0.001 |
| UAC (mg/g) | 1803.3±2861.2 | 555.9±1505.6 | 3213.4±3371.7 | 0.002 |
| Albuminuria | ||||
| None (%) | 24.5 | 46.2 | 0.0 | |
| Microalbuminuria (%) | 36.7 | 30.8 | 43.5 | 0.001 |
| Overt albuminuria (%) | 38.8 | 23.1 | 56.5 | |
| BMI (kg/m2) | 24.9±2.7 | 24.9±1.9 | 24.9±3.3 | 0.967 |
| Triglyceride (mg/dl) | 177.9±92.9 | 176.8±96.2 | 179.1±91.3 | 0.932 |
| LDL cholesterol (mg/dl) | 112.9±48.2 | 108.4±38.4 | 117.5±57.1 | 0.529 |
| HDL cholesterol (mg/dl) | 40.1±14.2 | 36.9±10.6 | 43.6±16.8 | 0.101 |
| Hemoglobin (g/dl) | 11.4±2.2 | 12.3±2.2 | 10.5±1.8 | 0.003 |
| Albumin (g/dl) | 3.8 ±0.7 | 3.9±0.6 | 3.5±0.7 | 0.021 |
| Calcium (mg/dl) | 8.6±1.1 | 8.6±1.4 | 8.6±0.7 | 0.876 |
| Phosphate (mg/dl) | 3.8±1.0 | 3.7±1.0 | 3.9±0.9 | 0.572 |
Abbreviations: BMI, body mass index; DA, disc area; DBP, diastolic blood pressure; DR, diabetic retinopathy; eGFR, estimated glomerular filtration rate; FA, fluorescein angiography; HDL, high-density lipoprotein; HTN, hypertension; LDL, low-density lipoprotein; SBP, systolic blood pressure; UAC, urine albumin creatinine ratio.
Note: values are expressed as the mean±SD.