Table 2.
Aberrant crypts in mice treated with blueberry juice (BJ) and azoxymethane (AOM).
| Group | Number of aberrant crypts | Mean ± SD | ||||||
|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | ||
| Water 15 μL/g |
0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
|
| ||||||||
| AOM 10 mg/kg |
57.14 ± 6.85 | 10 ± 1.44 | 3.28 ± 0.77 | 1.85 ± 0.41 | 0.14 ± 0.14 | 0.42 ± 0.42 | 0.42 ± 0.20 | 73.25 ± 1.44a |
|
| ||||||||
| BJ 15 μL/g |
1.71 ± 0.89 | 0.28 ± 0.18 | 0 | 0 | 0 | 0 | 0 | 1.99 ± 0.54 |
|
| ||||||||
| BJ + AOM 1.6 μL/g + 10 mg/kg |
23.17 ± 3.37 | 1.83 ± 0.71 | 0.66 ± 0.49 | 0.16 ± 0.17 | 0 | 0 | 0 | 25.82 ± 1.19a,b |
|
| ||||||||
| BJ + AOM 4.1 μL/g + 10 mg/kg |
8.5 ± 1.65 | 0.75 ± 0.37 | 0.37 ± 0.26 | 0.12 ± 0.13 | 0 | 0.12 ± 0.13 | 0 | 9.86 ± 0.51a,b |
|
| ||||||||
| BJ + AOM 15 μL/g + 10 mg/kg |
299.5 ± 43.14 | 12 ± 2.72 | 4.16 ± 1.09 | 1 ± 0.26 | 0.33 ± 0.21 | 0 | 0 | 316.99 ± 9.48a,b |
Values represent the mean ± SD obtained in the colon of 8 mice per group. aStatistically significant with respect to the mean control value and bwith respect to the value of the AOM treated group. ANOVA and Student-Newman-Keuls tests, P ≤ 0.05.