Table 2.

Necropsy results for mice that died after resection prior to day 21 (end of experiment)

Genotype	Diet	Cause of Death	Postoperative Day of Death
C57BL/6
WT littermates of tis7−/−	High-fat	Unknown (n =1 of 17 operated)	Day 6 (n = 1)
Tis7−/−	High-fat	Obstruction (n = 11)	Obstruction (n = 11): day 3 (n = 4), day 4 (n = 4), day 5 (n = 1), day 15 (n = 2)
		Dehiscence (n = 1)	Dehiscence: day 3 (n = 1)
		Anastomotic leak (n = 1)	Leak: day 4 (n = 1)
		No obvious cause (n = 4)	No obvious cause: day 3 (n = 2), day 4 (n = 1), day 7 (n = 1)
		<24 h (n = 1) (total n = 18 with early death of 24 operated)*
FVB/N
WT littermates of tis7tg	High-fat	Small bowel obstruction with hemorrhage (n = 4), hemorrhage (n = 2) (total n = 6 early death of 12 operated)	Obstruction with hemorrhage (n = 4): day 2 (n = 1), day 4 (n = 3)
			Hemorrhage (n = 2): day 2 (n = 2)
tis7tg	High-fat	Small bowel obstruction with hemorrhage (n = 2)	Obstruction with hemorrhage: day 3 (n = 1), day 4 (n= 1)
		Hemorrhage (n = 1) (total n = 3 early death of 13 operated)†	Hemorrhage: day 5 (n = 1)

n, Number of mice.

^*P = 0.0001 vs. WT. †P = 0.05 vs. WT.