Table 1.
Maximal internal diameters (in μm) for FA and arterioles in young and old mice
Young |
Old |
|||
---|---|---|---|---|
Vessel Branch | SNP | ACh | SNP | ACh |
FA | 57 ± 2 | 60 ± 2* | 61 ± 4 | 62 ± 5 |
1A | 50 ± 2 | 51 ± 2 | 55 ± 5 | 56 ± 5 |
2A | 35 ± 3 | 35 ± 2 | 44 ± 3 | 44 ± 4 |
3A | 23 ± 2 | 23 ± 1 | 32 ± 3 | 31 ± 4 |
Values are means ± SE; n = 5 per group. One vessel from each branch order was studied in each gluteus maximus muscle (GM) preparation. Maximal internal diameters were obtained during superfusion with 10−4 M sodium nitroprusside (SNP) and with 10−5 M ACh. Young, 4-mo-old male C57BL/6 mice; Old, 24-mo-old male C57BL/6 mice; FA, feed arteries; 1A, first-order arteriole; 2A, second-order arteriole; 3A, third-order arteriole.
P < 0.05, ACh vs. SNP.