Table 1.

Averaged cardiopulmonary chemoreflex responses to PBG (2–8 μg/kg) evoked under control conditions and during recovery

	Control				Recovery
PBG, μg/kg	MAP, Δ%	HR, Δbeats/min	RSNA, ∫Δ%	ASNA, ∫Δ%	MAP, ∫Δ%	HR, Δbeats/min	RSNA, ∫Δ%	ASNA, ∫Δ%
2	−6.6 ± 3.2	−11.8 ± 5.9	−9.5 ± 1.6	−7.6 ± 2.0	−5.6 ± 1.5	−12.7 ± 5.4	−10.5 ± 1.3	−6.8 ± 1.2
4	−14.7 ± 5.8	−34.9 ± 12.3	−20.7 ± 3.5	−17.0 ± 2.8	−8.8 ± 1.5	−29.5 ± 10.2	−20.1 ± 2.2	−11.6 ± 1.5
8	−23.0 ± 5.0	−57.1 ± 12.9	−35.0 ± 4.0	−24.2 ± 3.4	−14.0 ± 2.5*	−50.3 ± 11.3	−29.3 ± 2.9	−18.6 ± 2.5

Values are means ± SE. Control, control conditions; Recovery, ∼ 1 h after hemorrhage; PBG, phenylbiguanide; HR, heart rate; MAP, mean arterial pressure; RSNA, renal sympathetic nerve activity; ASNA, adrenal sympathetic nerve activity.

^*Significant difference vs. control (P < 0.05).